{"uniprot":"P13765","gene":"HLA-DOB","title":"HLA-DOB (HLA Class II Histocompatibility Antigen, DO Beta Chain)","length":273,"sequence":["MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC"],"topology":[{"pos":1,"topology":"sp"},{"pos":2,"topology":"sp"},{"pos":3,"topology":"sp"},{"pos":4,"topology":"sp"},{"pos":5,"topology":"sp"},{"pos":6,"topology":"sp"},{"pos":7,"topology":"sp"},{"pos":8,"topology":"sp"},{"pos":9,"topology":"sp"},{"pos":10,"topology":"sp"},{"pos":11,"topology":"sp"},{"pos":12,"topology":"sp"},{"pos":13,"topology":"sp"},{"pos":14,"topology":"sp"},{"pos":15,"topology":"sp"},{"pos":16,"topology":"sp"},{"pos":17,"topology":"sp"},{"pos":18,"topology":"sp"},{"pos":19,"topology":"sp"},{"pos":20,"topology":"sp"},{"pos":21,"topology":"sp"},{"pos":22,"topology":"sp"},{"pos":23,"topology":"sp"},{"pos":24,"topology":"sp"},{"pos":25,"topology":"sp"},{"pos":26,"topology":"sp"},{"pos":27,"topology":"outside"},{"pos":28,"topology":"outside"},{"pos":29,"topology":"outside"},{"pos":30,"topology":"outside"},{"pos":31,"topology":"outside"},{"pos":32,"topology":"outside"},{"pos":33,"topology":"outside"},{"pos":34,"topology":"outside"},{"pos":35,"topology":"outside"},{"pos":36,"topology":"outside"},{"pos":37,"topology":"outside"},{"pos":38,"topology":"outside"},{"pos":39,"topology":"outside"},{"pos":40,"topology":"outside"},{"pos":41,"topology":"outside"},{"pos":42,"topology":"outside"},{"pos":43,"topology":"outside"},{"pos":44,"topology":"outside"},{"pos":45,"topology":"outside"},{"pos":46,"topology":"outside"},{"pos":47,"topology":"outside"},{"pos":48,"topology":"outside"},{"pos":49,"topology":"outside"},{"pos":50,"topology":"outside"},{"pos":51,"topology":"outside"},{"pos":52,"topology":"outside"},{"pos":53,"topology":"outside"},{"pos":54,"topology":"outside"},{"pos":55,"topology":"outside"},{"pos":56,"topology":"outside"},{"pos":57,"topology":"outside"},{"pos":58,"topology":"outside"},{"pos":59,"topology":"outside"},{"pos":60,"topology":"outside"},{"pos":61,"topology":"outside"},{"pos":62,"topology":"outside"},{"pos":63,"topology":"outside"},{"pos":64,"topology":"outside"},{"pos":65,"topology":"outside"},{"pos":66,"topology":"outside"},{"pos":67,"topology":"outside"},{"pos":68,"topology":"outside"},{"pos":69,"topology":"outside"},{"pos":70,"topology":"outside"},{"pos":71,"topology":"outside"},{"pos":72,"topology":"outside"},{"pos":73,"topology":"outside"},{"pos":74,"topology":"outside"},{"pos":75,"topology":"outside"},{"pos":76,"topology":"outside"},{"pos":77,"topology":"outside"},{"pos":78,"topology":"outside"},{"pos":79,"topology":"outside"},{"pos":80,"topology":"outside"},{"pos":81,"topology":"outside"},{"pos":82,"topology":"outside"},{"pos":83,"topology":"outside"},{"pos":84,"topology":"outside"},{"pos":85,"topology":"outside"},{"pos":86,"topology":"outside"},{"pos":87,"topology":"outside"},{"pos":88,"topology":"outside"},{"pos":89,"topology":"outside"},{"pos":90,"topology":"outside"},{"pos":91,"topology":"outside"},{"pos":92,"topology":"outside"},{"pos":93,"topology":"outside"},{"pos":94,"topology":"outside"},{"pos":95,"topology":"outside"},{"pos":96,"topology":"outside"},{"pos":97,"topology":"outside"},{"pos":98,"topology":"outside"},{"pos":99,"topology":"outside"},{"pos":100,"topology":"outside"},{"pos":101,"topology":"outside"},{"pos":102,"topology":"outside"},{"pos":103,"topology":"outside"},{"pos":104,"topology":"outside"},{"pos":105,"topology":"outside"},{"pos":106,"topology":"outside"},{"pos":107,"topology":"outside"},{"pos":108,"topology":"outside"},{"pos":109,"topology":"outside"},{"pos":110,"topology":"outside"},{"pos":111,"topology":"outside"},{"pos":112,"topology":"outside"},{"pos":113,"topology":"outside"},{"pos":114,"topology":"outside"},{"pos":115,"topology":"outside"},{"pos":116,"topology":"outside"},{"pos":117,"topology":"outside"},{"pos":118,"topology":"outside"},{"pos":119,"topology":"outside"},{"pos":120,"topology":"outside"},{"pos":121,"topology":"outside"},{"pos":122,"topology":"outside"},{"pos":123,"topology":"outside"},{"pos":124,"topology":"outside"},{"pos":125,"topology":"outside"},{"pos":126,"topology":"outside"},{"pos":127,"topology":"outside"},{"pos":128,"topology":"outside"},{"pos":129,"topology":"outside"},{"pos":130,"topology":"outside"},{"pos":131,"topology":"outside"},{"pos":132,"topology":"outside"},{"pos":133,"topology":"outside"},{"pos":134,"topology":"outside"},{"pos":135,"topology":"outside"},{"pos":136,"topology":"outside"},{"pos":137,"topology":"outside"},{"pos":138,"topology":"outside"},{"pos":139,"topology":"outside"},{"pos":140,"topology":"outside"},{"pos":141,"topology":"outside"},{"pos":142,"topology":"outside"},{"pos":143,"topology":"outside"},{"pos":144,"topology":"outside"},{"pos":145,"topology":"outside"},{"pos":146,"topology":"outside"},{"pos":147,"topology":"outside"},{"pos":148,"topology":"outside"},{"pos":149,"topology":"outside"},{"pos":150,"topology":"outside"},{"pos":151,"topology":"outside"},{"pos":152,"topology":"outside"},{"pos":153,"topology":"outside"},{"pos":154,"topology":"outside"},{"pos":155,"topology":"outside"},{"pos":156,"topology":"outside"},{"pos":157,"topology":"outside"},{"pos":158,"topology":"outside"},{"pos":159,"topology":"outside"},{"pos":160,"topology":"outside"},{"pos":161,"topology":"outside"},{"pos":162,"topology":"outside"},{"pos":163,"topology":"outside"},{"pos":164,"topology":"outside"},{"pos":165,"topology":"outside"},{"pos":166,"topology":"outside"},{"pos":167,"topology":"outside"},{"pos":168,"topology":"outside"},{"pos":169,"topology":"outside"},{"pos":170,"topology":"outside"},{"pos":171,"topology":"outside"},{"pos":172,"topology":"outside"},{"pos":173,"topology":"outside"},{"pos":174,"topology":"outside"},{"pos":175,"topology":"outside"},{"pos":176,"topology":"outside"},{"pos":177,"topology":"outside"},{"pos":178,"topology":"outside"},{"pos":179,"topology":"outside"},{"pos":180,"topology":"outside"},{"pos":181,"topology":"outside"},{"pos":182,"topology":"outside"},{"pos":183,"topology":"outside"},{"pos":184,"topology":"outside"},{"pos":185,"topology":"outside"},{"pos":186,"topology":"outside"},{"pos":187,"topology":"outside"},{"pos":188,"topology":"outside"},{"pos":189,"topology":"outside"},{"pos":190,"topology":"outside"},{"pos":191,"topology":"outside"},{"pos":192,"topology":"outside"},{"pos":193,"topology":"outside"},{"pos":194,"topology":"outside"},{"pos":195,"topology":"outside"},{"pos":196,"topology":"outside"},{"pos":197,"topology":"outside"},{"pos":198,"topology":"outside"},{"pos":199,"topology":"outside"},{"pos":200,"topology":"outside"},{"pos":201,"topology":"outside"},{"pos":202,"topology":"outside"},{"pos":203,"topology":"outside"},{"pos":204,"topology":"outside"},{"pos":205,"topology":"outside"},{"pos":206,"topology":"outside"},{"pos":207,"topology":"outside"},{"pos":208,"topology":"outside"},{"pos":209,"topology":"outside"},{"pos":210,"topology":"outside"},{"pos":211,"topology":"outside"},{"pos":212,"topology":"outside"},{"pos":213,"topology":"outside"},{"pos":214,"topology":"outside"},{"pos":215,"topology":"outside"},{"pos":216,"topology":"outside"},{"pos":217,"topology":"outside"},{"pos":218,"topology":"outside"},{"pos":219,"topology":"outside"},{"pos":220,"topology":"outside"},{"pos":221,"topology":"outside"},{"pos":222,"topology":"outside"},{"pos":223,"topology":"outside"},{"pos":224,"topology":"outside"},{"pos":225,"topology":"membr"},{"pos":226,"topology":"membr"},{"pos":227,"topology":"membr"},{"pos":228,"topology":"membr"},{"pos":229,"topology":"membr"},{"pos":230,"topology":"membr"},{"pos":231,"topology":"membr"},{"pos":232,"topology":"membr"},{"pos":233,"topology":"membr"},{"pos":234,"topology":"membr"},{"pos":235,"topology":"membr"},{"pos":236,"topology":"membr"},{"pos":237,"topology":"membr"},{"pos":238,"topology":"membr"},{"pos":239,"topology":"membr"},{"pos":240,"topology":"membr"},{"pos":241,"topology":"membr"},{"pos":242,"topology":"membr"},{"pos":243,"topology":"membr"},{"pos":244,"topology":"membr"},{"pos":245,"topology":"membr"},{"pos":246,"topology":"inside"},{"pos":247,"topology":"inside"},{"pos":248,"topology":"inside"},{"pos":249,"topology":"inside"},{"pos":250,"topology":"inside"},{"pos":251,"topology":"inside"},{"pos":252,"topology":"inside"},{"pos":253,"topology":"inside"},{"pos":254,"topology":"inside"},{"pos":255,"topology":"inside"},{"pos":256,"topology":"inside"},{"pos":257,"topology":"inside"},{"pos":258,"topology":"inside"},{"pos":259,"topology":"inside"},{"pos":260,"topology":"inside"},{"pos":261,"topology":"inside"},{"pos":262,"topology":"inside"},{"pos":263,"topology":"inside"},{"pos":264,"topology":"inside"},{"pos":265,"topology":"inside"},{"pos":266,"topology":"inside"},{"pos":267,"topology":"inside"},{"pos":268,"topology":"inside"},{"pos":269,"topology":"inside"},{"pos":270,"topology":"inside"},{"pos":271,"topology":"inside"},{"pos":272,"topology":"inside"},{"pos":273,"topology":"inside"}],"curves":{"stringent":[{"pos":1,"prob":0.000041},{"pos":2,"prob":0.000111},{"pos":3,"prob":0.000181},{"pos":4,"prob":0.000543},{"pos":5,"prob":0.000905},{"pos":6,"prob":0.001859},{"pos":7,"prob":0.002812},{"pos":8,"prob":0.00878},{"pos":9,"prob":0.014748},{"pos":10,"prob":0.047009},{"pos":11,"prob":0.07927},{"pos":12,"prob":0.283383},{"pos":13,"prob":0.487495},{"pos":14,"prob":0.717105},{"pos":15,"prob":0.946714},{"pos":16,"prob":0.997389},{"pos":17,"prob":0.999547},{"pos":18,"prob":0.99994},{"pos":19,"prob":0.999989},{"pos":20,"prob":0.999996},{"pos":21,"prob":0.999999},{"pos":22,"prob":0.999999},{"pos":23,"prob":0.999999},{"pos":24,"prob":0.999999},{"pos":25,"prob":0.999999},{"pos":26,"prob":0.999999},{"pos":27,"prob":0.999999},{"pos":28,"prob":0.999999},{"pos":29,"prob":0.999999},{"pos":30,"prob":0.999999},{"pos":31,"prob":0.999995},{"pos":32,"prob":0.999971},{"pos":33,"prob":0.999955},{"pos":34,"prob":0.99888},{"pos":35,"prob":0.972002},{"pos":36,"prob":0.015512},{"pos":37,"prob":0.005872},{"pos":38,"prob":0.004893},{"pos":39,"prob":0.001063},{"pos":40,"prob":0.000731},{"pos":41,"prob":0.000515},{"pos":42,"prob":0.000291},{"pos":43,"prob":0.000251},{"pos":44,"prob":0.000139},{"pos":45,"prob":0.000095},{"pos":46,"prob":0.000095},{"pos":47,"prob":0.000139},{"pos":48,"prob":0.000241},{"pos":49,"prob":0.000251},{"pos":50,"prob":0.000241},{"pos":51,"prob":0.000241},{"pos":52,"prob":0.000226},{"pos":53,"prob":0.000139},{"pos":54,"prob":0.000039},{"pos":55,"prob":0.000039},{"pos":56,"prob":0.000063},{"pos":57,"prob":0.000203},{"pos":58,"prob":0.000226},{"pos":59,"prob":0.000241},{"pos":60,"prob":0.000286},{"pos":61,"prob":0.0003},{"pos":62,"prob":0.0003},{"pos":63,"prob":0.0003},{"pos":64,"prob":0.0003},{"pos":65,"prob":0.000989},{"pos":66,"prob":0.002035},{"pos":67,"prob":0.002247},{"pos":68,"prob":0.002807},{"pos":69,"prob":0.005955},{"pos":70,"prob":0.00641},{"pos":71,"prob":0.024409},{"pos":72,"prob":0.024409},{"pos":73,"prob":0.024409},{"pos":74,"prob":0.024409},{"pos":75,"prob":0.024409},{"pos":76,"prob":0.024409},{"pos":77,"prob":0.024409},{"pos":78,"prob":0.024409},{"pos":79,"prob":0.023538},{"pos":80,"prob":0.006731},{"pos":81,"prob":0.002971},{"pos":82,"prob":0.002614},{"pos":83,"prob":0.0018},{"pos":84,"prob":0.000554},{"pos":85,"prob":0.000512},{"pos":86,"prob":0.000434},{"pos":87,"prob":0.000208},{"pos":88,"prob":0.000157},{"pos":89,"prob":0.000157},{"pos":90,"prob":0.000157},{"pos":91,"prob":0.000157},{"pos":92,"prob":0.000114},{"pos":93,"prob":0.000113},{"pos":94,"prob":0.000113},{"pos":95,"prob":0.000113},{"pos":96,"prob":0.000114},{"pos":97,"prob":0.000114},{"pos":98,"prob":0.000151},{"pos":99,"prob":0.000233},{"pos":100,"prob":0.000254},{"pos":101,"prob":0.000259},{"pos":102,"prob":0.00027},{"pos":103,"prob":0.000387},{"pos":104,"prob":0.000794},{"pos":105,"prob":0.001259},{"pos":106,"prob":0.003049},{"pos":107,"prob":0.003601},{"pos":108,"prob":0.005466},{"pos":109,"prob":0.005733},{"pos":110,"prob":0.006861},{"pos":111,"prob":0.015992},{"pos":112,"prob":0.016158},{"pos":113,"prob":0.017343},{"pos":114,"prob":0.021904},{"pos":115,"prob":0.021904},{"pos":116,"prob":0.021904},{"pos":117,"prob":0.015992},{"pos":118,"prob":0.015992},{"pos":119,"prob":0.015992},{"pos":120,"prob":0.015992},{"pos":121,"prob":0.015992},{"pos":122,"prob":0.007676},{"pos":123,"prob":0.007128},{"pos":124,"prob":0.00169},{"pos":125,"prob":0.001414},{"pos":126,"prob":0.000519},{"pos":127,"prob":0.0002},{"pos":128,"prob":0.000094},{"pos":129,"prob":0.000075},{"pos":130,"prob":0.000027},{"pos":131,"prob":0.000026},{"pos":132,"prob":0.000011},{"pos":133,"prob":0.000011},{"pos":134,"prob":0.000011},{"pos":135,"prob":0.000011},{"pos":136,"prob":0.000011},{"pos":137,"prob":0.000011},{"pos":138,"prob":0.000011},{"pos":139,"prob":0.000011},{"pos":140,"prob":0.000049},{"pos":141,"prob":0.000079},{"pos":142,"prob":0.000097},{"pos":143,"prob":0.000145},{"pos":144,"prob":0.000168},{"pos":145,"prob":0.000486},{"pos":146,"prob":0.000887},{"pos":147,"prob":0.001336},{"pos":148,"prob":0.001761},{"pos":149,"prob":0.001936},{"pos":150,"prob":0.005618},{"pos":151,"prob":0.005618},{"pos":152,"prob":0.005618},{"pos":153,"prob":0.005618},{"pos":154,"prob":0.005618},{"pos":155,"prob":0.005618},{"pos":156,"prob":0.006659},{"pos":157,"prob":0.006659},{"pos":158,"prob":0.006659},{"pos":159,"prob":0.00509},{"pos":160,"prob":0.004601},{"pos":161,"prob":0.004601},{"pos":162,"prob":0.004601},{"pos":163,"prob":0.004601},{"pos":164,"prob":0.004601},{"pos":165,"prob":0.003698},{"pos":166,"prob":0.003698},{"pos":167,"prob":0.003698},{"pos":168,"prob":0.003698},{"pos":169,"prob":0.003698},{"pos":170,"prob":0.003698},{"pos":171,"prob":0.002527},{"pos":172,"prob":0.002302},{"pos":173,"prob":0.001518},{"pos":174,"prob":0.000805},{"pos":175,"prob":0.000583},{"pos":176,"prob":0.000372},{"pos":177,"prob":0.000348},{"pos":178,"prob":0.000334},{"pos":179,"prob":0.00033},{"pos":180,"prob":0.000316},{"pos":181,"prob":0.000297},{"pos":182,"prob":0.000231},{"pos":183,"prob":0.000165},{"pos":184,"prob":0.000095},{"pos":185,"prob":0.000048},{"pos":186,"prob":0.000048},{"pos":187,"prob":0.000048},{"pos":188,"prob":0.000048},{"pos":189,"prob":0.000048},{"pos":190,"prob":0.000048},{"pos":191,"prob":0.000048},{"pos":192,"prob":0.000048},{"pos":193,"prob":0.000194},{"pos":194,"prob":0.000419},{"pos":195,"prob":0.000663},{"pos":196,"prob":0.001789},{"pos":197,"prob":0.002715},{"pos":198,"prob":0.006959},{"pos":199,"prob":0.01036},{"pos":200,"prob":0.029536},{"pos":201,"prob":0.029536},{"pos":202,"prob":0.029536},{"pos":203,"prob":0.029536},{"pos":204,"prob":0.029536},{"pos":205,"prob":0.029536},{"pos":206,"prob":0.029536},{"pos":207,"prob":0.029536},{"pos":208,"prob":0.028084},{"pos":209,"prob":0.023556},{"pos":210,"prob":0.0046},{"pos":211,"prob":0.001548},{"pos":212,"prob":0.000761},{"pos":213,"prob":0.000364},{"pos":214,"prob":0.000113},{"pos":215,"prob":6.650983e-06},{"pos":216,"prob":1.197881e-06},{"pos":217,"prob":2.723739e-07},{"pos":218,"prob":3.715109e-08},{"pos":219,"prob":2.283301e-08},{"pos":220,"prob":2.539681e-09},{"pos":221,"prob":1.537706e-09},{"pos":222,"prob":3.177238e-10},{"pos":223,"prob":1.744037e-10},{"pos":224,"prob":2.344558e-11},{"pos":225,"prob":9.87701e-13},{"pos":226,"prob":9.87701e-13},{"pos":227,"prob":8.174519e-13},{"pos":228,"prob":8.174519e-13},{"pos":229,"prob":4.783841e-13},{"pos":230,"prob":4.783841e-13},{"pos":231,"prob":4.783841e-13},{"pos":232,"prob":4.783841e-13},{"pos":233,"prob":4.783841e-13},{"pos":234,"prob":8.174519e-13},{"pos":235,"prob":8.548427e-13},{"pos":236,"prob":1.412856e-12},{"pos":237,"prob":1.830325e-12},{"pos":238,"prob":2.208539e-12},{"pos":239,"prob":2.733509e-12},{"pos":240,"prob":3.370383e-12},{"pos":241,"prob":3.628344e-11},{"pos":242,"prob":7.266928e-11},{"pos":243,"prob":1.006107e-10},{"pos":244,"prob":7.486049e-10},{"pos":245,"prob":8.822202e-10},{"pos":246,"prob":9.569874e-10},{"pos":247,"prob":2.128262e-09},{"pos":248,"prob":3.948674e-09},{"pos":249,"prob":2.517689e-08},{"pos":250,"prob":3.368263e-08},{"pos":251,"prob":6.706043e-08},{"pos":252,"prob":6.873864e-08},{"pos":253,"prob":1.823599e-07},{"pos":254,"prob":2.041321e-07},{"pos":255,"prob":2.386323e-07},{"pos":256,"prob":5.932398e-07},{"pos":257,"prob":7.182338e-07},{"pos":258,"prob":1.409219e-06},{"pos":259,"prob":3.226788e-06},{"pos":260,"prob":3.387157e-06},{"pos":261,"prob":3.547527e-06},{"pos":262,"prob":5.200085e-06},{"pos":263,"prob":6.852644e-06},{"pos":264,"prob":7.508961e-06},{"pos":265,"prob":8.165279e-06},{"pos":266,"prob":0.00001},{"pos":267,"prob":0.000012},{"pos":268,"prob":0.000016},{"pos":269,"prob":0.00002},{"pos":270,"prob":0.00002},{"pos":271,"prob":0.00002},{"pos":272,"prob":0.000016},{"pos":273,"prob":0.000012}],"moderate":[{"pos":1,"prob":0.000041},{"pos":2,"prob":0.000111},{"pos":3,"prob":0.000181},{"pos":4,"prob":0.000543},{"pos":5,"prob":0.000905},{"pos":6,"prob":0.001859},{"pos":7,"prob":0.002812},{"pos":8,"prob":0.00878},{"pos":9,"prob":0.014748},{"pos":10,"prob":0.047009},{"pos":11,"prob":0.07927},{"pos":12,"prob":0.283383},{"pos":13,"prob":0.487495},{"pos":14,"prob":0.717105},{"pos":15,"prob":0.946714},{"pos":16,"prob":0.997389},{"pos":17,"prob":0.999547},{"pos":18,"prob":0.99994},{"pos":19,"prob":0.999989},{"pos":20,"prob":0.999996},{"pos":21,"prob":0.999999},{"pos":22,"prob":0.999999},{"pos":23,"prob":0.999999},{"pos":24,"prob":0.999999},{"pos":25,"prob":0.999999},{"pos":26,"prob":0.999999},{"pos":27,"prob":0.999999},{"pos":28,"prob":0.999999},{"pos":29,"prob":0.999999},{"pos":30,"prob":0.999999},{"pos":31,"prob":0.999995},{"pos":32,"prob":0.999971},{"pos":33,"prob":0.999955},{"pos":34,"prob":0.99888},{"pos":35,"prob":0.972002},{"pos":36,"prob":0.015512},{"pos":37,"prob":0.005872},{"pos":38,"prob":0.004893},{"pos":39,"prob":0.001063},{"pos":40,"prob":0.000731},{"pos":41,"prob":0.000515},{"pos":42,"prob":0.000291},{"pos":43,"prob":0.000251},{"pos":44,"prob":0.000139},{"pos":45,"prob":0.000095},{"pos":46,"prob":0.000095},{"pos":47,"prob":0.000139},{"pos":48,"prob":0.000241},{"pos":49,"prob":0.000251},{"pos":50,"prob":0.000241},{"pos":51,"prob":0.000241},{"pos":52,"prob":0.000226},{"pos":53,"prob":0.000139},{"pos":54,"prob":0.000039},{"pos":55,"prob":0.000039},{"pos":56,"prob":0.000063},{"pos":57,"prob":0.000203},{"pos":58,"prob":0.000226},{"pos":59,"prob":0.000241},{"pos":60,"prob":0.000286},{"pos":61,"prob":0.0003},{"pos":62,"prob":0.0003},{"pos":63,"prob":0.0003},{"pos":64,"prob":0.0003},{"pos":65,"prob":0.000989},{"pos":66,"prob":0.002035},{"pos":67,"prob":0.002247},{"pos":68,"prob":0.002807},{"pos":69,"prob":0.005955},{"pos":70,"prob":0.00641},{"pos":71,"prob":0.024409},{"pos":72,"prob":0.024409},{"pos":73,"prob":0.024409},{"pos":74,"prob":0.024409},{"pos":75,"prob":0.024409},{"pos":76,"prob":0.024409},{"pos":77,"prob":0.024409},{"pos":78,"prob":0.024409},{"pos":79,"prob":0.023538},{"pos":80,"prob":0.006731},{"pos":81,"prob":0.002971},{"pos":82,"prob":0.002614},{"pos":83,"prob":0.0018},{"pos":84,"prob":0.000554},{"pos":85,"prob":0.000512},{"pos":86,"prob":0.000434},{"pos":87,"prob":0.000208},{"pos":88,"prob":0.000157},{"pos":89,"prob":0.000157},{"pos":90,"prob":0.000157},{"pos":91,"prob":0.000157},{"pos":92,"prob":0.000114},{"pos":93,"prob":0.000113},{"pos":94,"prob":0.000113},{"pos":95,"prob":0.000113},{"pos":96,"prob":0.000114},{"pos":97,"prob":0.000114},{"pos":98,"prob":0.000151},{"pos":99,"prob":0.000233},{"pos":100,"prob":0.000254},{"pos":101,"prob":0.000259},{"pos":102,"prob":0.00027},{"pos":103,"prob":0.000387},{"pos":104,"prob":0.000794},{"pos":105,"prob":0.001259},{"pos":106,"prob":0.003049},{"pos":107,"prob":0.003601},{"pos":108,"prob":0.005466},{"pos":109,"prob":0.005733},{"pos":110,"prob":0.006861},{"pos":111,"prob":0.015992},{"pos":112,"prob":0.016158},{"pos":113,"prob":0.017343},{"pos":114,"prob":0.021904},{"pos":115,"prob":0.021904},{"pos":116,"prob":0.021904},{"pos":117,"prob":0.015992},{"pos":118,"prob":0.015992},{"pos":119,"prob":0.015992},{"pos":120,"prob":0.015992},{"pos":121,"prob":0.015992},{"pos":122,"prob":0.007676},{"pos":123,"prob":0.007128},{"pos":124,"prob":0.00169},{"pos":125,"prob":0.001414},{"pos":126,"prob":0.000519},{"pos":127,"prob":0.0002},{"pos":128,"prob":0.000094},{"pos":129,"prob":0.000075},{"pos":130,"prob":0.000027},{"pos":131,"prob":0.000026},{"pos":132,"prob":0.000011},{"pos":133,"prob":0.000011},{"pos":134,"prob":0.000011},{"pos":135,"prob":0.000011},{"pos":136,"prob":0.000011},{"pos":137,"prob":0.000011},{"pos":138,"prob":0.000011},{"pos":139,"prob":0.000011},{"pos":140,"prob":0.000049},{"pos":141,"prob":0.000079},{"pos":142,"prob":0.000097},{"pos":143,"prob":0.000145},{"pos":144,"prob":0.000168},{"pos":145,"prob":0.000486},{"pos":146,"prob":0.000887},{"pos":147,"prob":0.001336},{"pos":148,"prob":0.001761},{"pos":149,"prob":0.001936},{"pos":150,"prob":0.005618},{"pos":151,"prob":0.005618},{"pos":152,"prob":0.005618},{"pos":153,"prob":0.005618},{"pos":154,"prob":0.005618},{"pos":155,"prob":0.005618},{"pos":156,"prob":0.006659},{"pos":157,"prob":0.006659},{"pos":158,"prob":0.006659},{"pos":159,"prob":0.00509},{"pos":160,"prob":0.004601},{"pos":161,"prob":0.004601},{"pos":162,"prob":0.004601},{"pos":163,"prob":0.004601},{"pos":164,"prob":0.004601},{"pos":165,"prob":0.003698},{"pos":166,"prob":0.003698},{"pos":167,"prob":0.003698},{"pos":168,"prob":0.003698},{"pos":169,"prob":0.003698},{"pos":170,"prob":0.003698},{"pos":171,"prob":0.002527},{"pos":172,"prob":0.002302},{"pos":173,"prob":0.001518},{"pos":174,"prob":0.000805},{"pos":175,"prob":0.000583},{"pos":176,"prob":0.000372},{"pos":177,"prob":0.000348},{"pos":178,"prob":0.000334},{"pos":179,"prob":0.00033},{"pos":180,"prob":0.000316},{"pos":181,"prob":0.000297},{"pos":182,"prob":0.000231},{"pos":183,"prob":0.000165},{"pos":184,"prob":0.000095},{"pos":185,"prob":0.000048},{"pos":186,"prob":0.000048},{"pos":187,"prob":0.000048},{"pos":188,"prob":0.000048},{"pos":189,"prob":0.000048},{"pos":190,"prob":0.000048},{"pos":191,"prob":0.000048},{"pos":192,"prob":0.000048},{"pos":193,"prob":0.000194},{"pos":194,"prob":0.000419},{"pos":195,"prob":0.000663},{"pos":196,"prob":0.001789},{"pos":197,"prob":0.002715},{"pos":198,"prob":0.006959},{"pos":199,"prob":0.01036},{"pos":200,"prob":0.029536},{"pos":201,"prob":0.029536},{"pos":202,"prob":0.029536},{"pos":203,"prob":0.029536},{"pos":204,"prob":0.029536},{"pos":205,"prob":0.029536},{"pos":206,"prob":0.029536},{"pos":207,"prob":0.029536},{"pos":208,"prob":0.028084},{"pos":209,"prob":0.023556},{"pos":210,"prob":0.0046},{"pos":211,"prob":0.001548},{"pos":212,"prob":0.000761},{"pos":213,"prob":0.000364},{"pos":214,"prob":0.000113},{"pos":215,"prob":6.650983e-06},{"pos":216,"prob":1.197881e-06},{"pos":217,"prob":2.723739e-07},{"pos":218,"prob":3.715109e-08},{"pos":219,"prob":2.283301e-08},{"pos":220,"prob":2.539681e-09},{"pos":221,"prob":1.537706e-09},{"pos":222,"prob":3.177238e-10},{"pos":223,"prob":1.744037e-10},{"pos":224,"prob":2.344558e-11},{"pos":225,"prob":9.87701e-13},{"pos":226,"prob":9.87701e-13},{"pos":227,"prob":8.174519e-13},{"pos":228,"prob":8.174519e-13},{"pos":229,"prob":4.783841e-13},{"pos":230,"prob":4.783841e-13},{"pos":231,"prob":4.783841e-13},{"pos":232,"prob":4.783841e-13},{"pos":233,"prob":4.783841e-13},{"pos":234,"prob":8.174519e-13},{"pos":235,"prob":8.548427e-13},{"pos":236,"prob":1.412856e-12},{"pos":237,"prob":1.830325e-12},{"pos":238,"prob":2.208539e-12},{"pos":239,"prob":2.733509e-12},{"pos":240,"prob":3.370383e-12},{"pos":241,"prob":3.628344e-11},{"pos":242,"prob":7.266928e-11},{"pos":243,"prob":1.006107e-10},{"pos":244,"prob":7.486049e-10},{"pos":245,"prob":8.822202e-10},{"pos":246,"prob":9.569874e-10},{"pos":247,"prob":2.128262e-09},{"pos":248,"prob":3.948674e-09},{"pos":249,"prob":2.517689e-08},{"pos":250,"prob":3.368263e-08},{"pos":251,"prob":6.706043e-08},{"pos":252,"prob":6.873864e-08},{"pos":253,"prob":1.823599e-07},{"pos":254,"prob":2.041321e-07},{"pos":255,"prob":2.386323e-07},{"pos":256,"prob":5.932398e-07},{"pos":257,"prob":7.182338e-07},{"pos":258,"prob":1.409219e-06},{"pos":259,"prob":3.226788e-06},{"pos":260,"prob":3.387157e-06},{"pos":261,"prob":3.547527e-06},{"pos":262,"prob":5.200085e-06},{"pos":263,"prob":6.852644e-06},{"pos":264,"prob":7.508961e-06},{"pos":265,"prob":8.165279e-06},{"pos":266,"prob":0.00001},{"pos":267,"prob":0.000012},{"pos":268,"prob":0.000016},{"pos":269,"prob":0.00002},{"pos":270,"prob":0.00002},{"pos":271,"prob":0.00002},{"pos":272,"prob":0.000016},{"pos":273,"prob":0.000012}],"permissive":[{"pos":1,"prob":0.000041},{"pos":2,"prob":0.000111},{"pos":3,"prob":0.000181},{"pos":4,"prob":0.000543},{"pos":5,"prob":0.000905},{"pos":6,"prob":0.001859},{"pos":7,"prob":0.002812},{"pos":8,"prob":0.00878},{"pos":9,"prob":0.014748},{"pos":10,"prob":0.047009},{"pos":11,"prob":0.07927},{"pos":12,"prob":0.283383},{"pos":13,"prob":0.487495},{"pos":14,"prob":0.717105},{"pos":15,"prob":0.946714},{"pos":16,"prob":0.997389},{"pos":17,"prob":0.999547},{"pos":18,"prob":0.99994},{"pos":19,"prob":0.999989},{"pos":20,"prob":0.999996},{"pos":21,"prob":0.999999},{"pos":22,"prob":0.999999},{"pos":23,"prob":0.999999},{"pos":24,"prob":0.999999},{"pos":25,"prob":0.999999},{"pos":26,"prob":0.999999},{"pos":27,"prob":0.999999},{"pos":28,"prob":0.999999},{"pos":29,"prob":0.999999},{"pos":30,"prob":0.999999},{"pos":31,"prob":0.999995},{"pos":32,"prob":0.999971},{"pos":33,"prob":0.999955},{"pos":34,"prob":0.99888},{"pos":35,"prob":0.972002},{"pos":36,"prob":0.015512},{"pos":37,"prob":0.005872},{"pos":38,"prob":0.004893},{"pos":39,"prob":0.001063},{"pos":40,"prob":0.000731},{"pos":41,"prob":0.000515},{"pos":42,"prob":0.000291},{"pos":43,"prob":0.000251},{"pos":44,"prob":0.000139},{"pos":45,"prob":0.000095},{"pos":46,"prob":0.000095},{"pos":47,"prob":0.000139},{"pos":48,"prob":0.000241},{"pos":49,"prob":0.000251},{"pos":50,"prob":0.000241},{"pos":51,"prob":0.000241},{"pos":52,"prob":0.000226},{"pos":53,"prob":0.000139},{"pos":54,"prob":0.000039},{"pos":55,"prob":0.000039},{"pos":56,"prob":0.000063},{"pos":57,"prob":0.000203},{"pos":58,"prob":0.000226},{"pos":59,"prob":0.000241},{"pos":60,"prob":0.000286},{"pos":61,"prob":0.0003},{"pos":62,"prob":0.0003},{"pos":63,"prob":0.0003},{"pos":64,"prob":0.0003},{"pos":65,"prob":0.000989},{"pos":66,"prob":0.002035},{"pos":67,"prob":0.002247},{"pos":68,"prob":0.002807},{"pos":69,"prob":0.005955},{"pos":70,"prob":0.00641},{"pos":71,"prob":0.024409},{"pos":72,"prob":0.024409},{"pos":73,"prob":0.024409},{"pos":74,"prob":0.024409},{"pos":75,"prob":0.024409},{"pos":76,"prob":0.024409},{"pos":77,"prob":0.024409},{"pos":78,"prob":0.024409},{"pos":79,"prob":0.023538},{"pos":80,"prob":0.006731},{"pos":81,"prob":0.002971},{"pos":82,"prob":0.002614},{"pos":83,"prob":0.0018},{"pos":84,"prob":0.000554},{"pos":85,"prob":0.000512},{"pos":86,"prob":0.000434},{"pos":87,"prob":0.000208},{"pos":88,"prob":0.000157},{"pos":89,"prob":0.000157},{"pos":90,"prob":0.000157},{"pos":91,"prob":0.000157},{"pos":92,"prob":0.000114},{"pos":93,"prob":0.000113},{"pos":94,"prob":0.000113},{"pos":95,"prob":0.000113},{"pos":96,"prob":0.000114},{"pos":97,"prob":0.000114},{"pos":98,"prob":0.000151},{"pos":99,"prob":0.000233},{"pos":100,"prob":0.000254},{"pos":101,"prob":0.000259},{"pos":102,"prob":0.00027},{"pos":103,"prob":0.000387},{"pos":104,"prob":0.000794},{"pos":105,"prob":0.001259},{"pos":106,"prob":0.003049},{"pos":107,"prob":0.003601},{"pos":108,"prob":0.005466},{"pos":109,"prob":0.005733},{"pos":110,"prob":0.006861},{"pos":111,"prob":0.015992},{"pos":112,"prob":0.016158},{"pos":113,"prob":0.017343},{"pos":114,"prob":0.021904},{"pos":115,"prob":0.021904},{"pos":116,"prob":0.021904},{"pos":117,"prob":0.015992},{"pos":118,"prob":0.015992},{"pos":119,"prob":0.015992},{"pos":120,"prob":0.015992},{"pos":121,"prob":0.015992},{"pos":122,"prob":0.007676},{"pos":123,"prob":0.007128},{"pos":124,"prob":0.00169},{"pos":125,"prob":0.001414},{"pos":126,"prob":0.000519},{"pos":127,"prob":0.0002},{"pos":128,"prob":0.000094},{"pos":129,"prob":0.000075},{"pos":130,"prob":0.000027},{"pos":131,"prob":0.000026},{"pos":132,"prob":0.000011},{"pos":133,"prob":0.000011},{"pos":134,"prob":0.000011},{"pos":135,"prob":0.000011},{"pos":136,"prob":0.000011},{"pos":137,"prob":0.000011},{"pos":138,"prob":0.000011},{"pos":139,"prob":0.000011},{"pos":140,"prob":0.000049},{"pos":141,"prob":0.000079},{"pos":142,"prob":0.000097},{"pos":143,"prob":0.000145},{"pos":144,"prob":0.000168},{"pos":145,"prob":0.000486},{"pos":146,"prob":0.000887},{"pos":147,"prob":0.001336},{"pos":148,"prob":0.001761},{"pos":149,"prob":0.001936},{"pos":150,"prob":0.005618},{"pos":151,"prob":0.005618},{"pos":152,"prob":0.005618},{"pos":153,"prob":0.005618},{"pos":154,"prob":0.005618},{"pos":155,"prob":0.005618},{"pos":156,"prob":0.006659},{"pos":157,"prob":0.006659},{"pos":158,"prob":0.006659},{"pos":159,"prob":0.00509},{"pos":160,"prob":0.004601},{"pos":161,"prob":0.004601},{"pos":162,"prob":0.004601},{"pos":163,"prob":0.004601},{"pos":164,"prob":0.004601},{"pos":165,"prob":0.003698},{"pos":166,"prob":0.003698},{"pos":167,"prob":0.003698},{"pos":168,"prob":0.003698},{"pos":169,"prob":0.003698},{"pos":170,"prob":0.003698},{"pos":171,"prob":0.002527},{"pos":172,"prob":0.002302},{"pos":173,"prob":0.001518},{"pos":174,"prob":0.000805},{"pos":175,"prob":0.000583},{"pos":176,"prob":0.000372},{"pos":177,"prob":0.000348},{"pos":178,"prob":0.000334},{"pos":179,"prob":0.00033},{"pos":180,"prob":0.000316},{"pos":181,"prob":0.000297},{"pos":182,"prob":0.000231},{"pos":183,"prob":0.000165},{"pos":184,"prob":0.000095},{"pos":185,"prob":0.000048},{"pos":186,"prob":0.000048},{"pos":187,"prob":0.000048},{"pos":188,"prob":0.000048},{"pos":189,"prob":0.000048},{"pos":190,"prob":0.000048},{"pos":191,"prob":0.000048},{"pos":192,"prob":0.000048},{"pos":193,"prob":0.000194},{"pos":194,"prob":0.000419},{"pos":195,"prob":0.000663},{"pos":196,"prob":0.001789},{"pos":197,"prob":0.002715},{"pos":198,"prob":0.006959},{"pos":199,"prob":0.01036},{"pos":200,"prob":0.029536},{"pos":201,"prob":0.029536},{"pos":202,"prob":0.029536},{"pos":203,"prob":0.029536},{"pos":204,"prob":0.029536},{"pos":205,"prob":0.029536},{"pos":206,"prob":0.029536},{"pos":207,"prob":0.029536},{"pos":208,"prob":0.028084},{"pos":209,"prob":0.023556},{"pos":210,"prob":0.0046},{"pos":211,"prob":0.001548},{"pos":212,"prob":0.000761},{"pos":213,"prob":0.000364},{"pos":214,"prob":0.000113},{"pos":215,"prob":6.650983e-06},{"pos":216,"prob":1.197881e-06},{"pos":217,"prob":2.723739e-07},{"pos":218,"prob":3.715109e-08},{"pos":219,"prob":2.283301e-08},{"pos":220,"prob":2.539681e-09},{"pos":221,"prob":1.537706e-09},{"pos":222,"prob":3.177238e-10},{"pos":223,"prob":1.744037e-10},{"pos":224,"prob":2.344558e-11},{"pos":225,"prob":9.87701e-13},{"pos":226,"prob":9.87701e-13},{"pos":227,"prob":8.174519e-13},{"pos":228,"prob":8.174519e-13},{"pos":229,"prob":4.783841e-13},{"pos":230,"prob":4.783841e-13},{"pos":231,"prob":4.783841e-13},{"pos":232,"prob":4.783841e-13},{"pos":233,"prob":4.783841e-13},{"pos":234,"prob":8.174519e-13},{"pos":235,"prob":8.548427e-13},{"pos":236,"prob":1.412856e-12},{"pos":237,"prob":1.830325e-12},{"pos":238,"prob":2.208539e-12},{"pos":239,"prob":2.733509e-12},{"pos":240,"prob":3.370383e-12},{"pos":241,"prob":3.628344e-11},{"pos":242,"prob":7.266928e-11},{"pos":243,"prob":1.006107e-10},{"pos":244,"prob":7.486049e-10},{"pos":245,"prob":8.822202e-10},{"pos":246,"prob":9.569874e-10},{"pos":247,"prob":2.128262e-09},{"pos":248,"prob":3.948674e-09},{"pos":249,"prob":2.517689e-08},{"pos":250,"prob":3.368263e-08},{"pos":251,"prob":6.706043e-08},{"pos":252,"prob":6.873864e-08},{"pos":253,"prob":1.823599e-07},{"pos":254,"prob":2.041321e-07},{"pos":255,"prob":2.386323e-07},{"pos":256,"prob":5.932398e-07},{"pos":257,"prob":7.182338e-07},{"pos":258,"prob":1.409219e-06},{"pos":259,"prob":3.226788e-06},{"pos":260,"prob":3.387157e-06},{"pos":261,"prob":3.547527e-06},{"pos":262,"prob":5.200085e-06},{"pos":263,"prob":6.852644e-06},{"pos":264,"prob":7.508961e-06},{"pos":265,"prob":8.165279e-06},{"pos":266,"prob":0.00001},{"pos":267,"prob":0.000012},{"pos":268,"prob":0.000016},{"pos":269,"prob":0.00002},{"pos":270,"prob":0.00002},{"pos":271,"prob":0.00002},{"pos":272,"prob":0.000016},{"pos":273,"prob":0.000012}]},"peaks":{"stringent":[{"peak_position":25,"peak_height":0.999999,"prominence":0.996936,"width":22.503077,"left_ip":11.983493,"right_ip":34.48657,"left_ip_0.9":8.656238,"right_ip_0.9":37.043849,"left_ip_0.75":10.255604,"right_ip_0.75":35.847521,"left_ip_1.0":3,"right_ip_1.0":40.250284,"octamer":"SMTQ|GTDS"}],"moderate":[{"peak_position":25,"peak_height":0.999999,"prominence":0.996936,"width":22.503077,"left_ip":11.983493,"right_ip":34.48657,"left_ip_0.9":8.656238,"right_ip_0.9":37.043849,"left_ip_0.75":10.255604,"right_ip_0.75":35.847521,"left_ip_1.0":3,"right_ip_1.0":40.250284,"octamer":"SMTQ|GTDS"}],"permissive":[{"peak_position":25,"peak_height":0.999999,"prominence":0.996936,"width":22.503077,"left_ip":11.983493,"right_ip":34.48657,"left_ip_0.9":8.656238,"right_ip_0.9":37.043849,"left_ip_0.75":10.255604,"right_ip_0.75":35.847521,"left_ip_1.0":3,"right_ip_1.0":40.250284,"octamer":"SMTQ|GTDS"},{"peak_position":75,"peak_height":0.023962,"prominence":0.023847,"width":10.130557,"left_ip":68.845375,"right_ip":78.975932,"left_ip_0.9":65.21385,"right_ip_0.9":82.191617,"left_ip_0.75":67.147348,"right_ip_0.75":80.576125,"left_ip_1.0":54,"right_ip_1.0":128.633449,"octamer":"MFVA|LTKL"},{"peak_position":115,"peak_height":0.019315,"prominence":0.019194,"width":12.078235,"left_ip":108.841069,"right_ip":120.919305,"left_ip_0.9":103.985843,"right_ip_0.9":124.524927,"left_ip_0.75":106.473722,"right_ip_0.75":122.823231,"left_ip_1.0":54.270041,"right_ip_1.0":128.583087,"octamer":"GAPF|TVGR"},{"peak_position":204,"peak_height":0.029144,"prominence":0.029132,"width":10.7071,"left_ip":197.799315,"right_ip":208.506415,"left_ip_0.9":194.56892,"right_ip_0.9":211.37704,"left_ip_0.75":196.195083,"right_ip_0.75":209.961266,"left_ip_1.0":134,"right_ip_1.0":216.897226,"octamer":"VDHS|SLLS"}]},"domains":{"uniprot":[{"start":123,"end":213,"name":"Ig-like C1-type"}],"ted":[{"start":34,"end":114,"name":"high"},{"start":123,"end":214,"name":"high"}],"interpro_domain":[{"start":40,"end":112,"name":"MHC class II, beta chain, N-terminal"},{"start":39,"end":113,"name":"MHC class II, beta chain, N-terminal"},{"start":125,"end":206,"name":"Immunoglobulin C1-set"},{"start":138,"end":209,"name":"Immunoglobulin C1-set"},{"start":123,"end":213,"name":"Immunoglobulin-like domain"}],"interpro_superfamily":[{"start":3,"end":119,"name":"MHC classes I/II-like antigen recognition protein"},{"start":119,"end":226,"name":"Immunoglobulin-like fold"},{"start":2,"end":117,"name":"MHC class II, alpha/beta chain, N-terminal"},{"start":119,"end":215,"name":"Immunoglobulin-like domain superfamily"}],"pfam":[{"start":40,"end":112,"name":"MHC class II, beta chain, N-terminal"},{"start":125,"end":206,"name":"Immunoglobulin C1-set"}],"smart":[{"start":39,"end":113,"name":"MHC class II, beta chain, N-terminal"},{"start":138,"end":209,"name":"Immunoglobulin C1-set"}]},"cleavages":[{"pos":26,"pos_p1":26,"source":"uniprot","citation":"","pmid":"","doi":"","protease":"","protease_uniprot":"","uniprot_feature_type":"signal_peptide","uniprot_description":"Signal peptidase","merops_protease_code":"","merops_cleavage_type":"","merops_method":"","topfind_method":"","weeks_method":"","schaeffer_cell_types":""}]}