UniProt · Membrane protein

INSR (Insulin Receptor)

P06213 · 1382 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·11 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

4 unique positions · 11 annotations · 4/4 (100%) covered by peaks

Sources (filter in the plot above): meropsuniprot

P1 pos	Sources	Proteases	References
`27`	meropsuniprot	XS26.001 , Signal peptidase	2983222 2211730 8257688
`758`	uniprot	Insulin receptor subunit alpha	—
`762`	merops	FURIN , PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7	7929288 18505722
`763`	uniprot	Insulin receptor subunit beta	—

1382 aa

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