HSA Human Sheddome Atlas
UniProt · Membrane protein

ITGAV (Integrin Alpha-v)

P06756 · 1048 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·18 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

15 unique positions · 18 annotations · 10/15 (67%) covered by peaks
Sources (filter in the plot above): merops+uniprotschaeffer22ascent+weeks21uniprotmeropsweeks21
P1 pos Sources Proteases References
30 merops+uniprotschaeffer22 XS26.001 2467745 36313159
51 schaeffer22 36313159
78 schaeffer22 36313159
233 ascent+weeks21 33536314
428 schaeffer22 36313159
765 schaeffer22 36313159
766 schaeffer22 36313159
889 uniprot Integrin alpha-V heavy chain
890 meropsschaeffer22 FURIN 18505722 36313159
891 uniprotmerops Integrin alpha-V light chain , MMP14 11741954
892 schaeffer22 36313159
893 schaeffer22 36313159
932 weeks21 33536314
951 ascent+weeks21 33536314
957 weeks21 33536314

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Sequence

1048 aa
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