UniProt · Membrane protein

FURIN (Furin)

P09958 · 794 aa ·Signal peptide ·Propeptide ·1× TM · 6 predicted cleavages ·19 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

7 unique positions · 19 annotations · 1/7 (14%) covered by peaks

Sources (filter in the plot above): uniprotmeropsmerops+uniprotpaper

P1 pos	Sources	Proteases	References
`26`	uniprot	Signal peptidase	—
`70`	merops	FURIN	—
`75`	meropsuniprot	M10.039 , FURIN , PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7 , Cleavage, second; by autolysis	24698179 18505722 9130696
`89`	merops	M10.039	24698179
`104`	merops	FURIN	1629222
`107`	meropsmerops+uniprot	PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7 , FURIN	18505722 1629222 9130696
`682`	paper	—	11237874 12220680

794 aa

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