HSA Human Sheddome Atlas
UniProt · Membrane protein

AREG (Amphiregulin)

P15514 · 252 aa ·Signal peptide ·Propeptide · 1 predicted cleavages ·8 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

6 unique positions · 8 annotations · 4/6 (67%) covered by peaks
Sources (filter in the plot above): uniprotpmapmerops+pmap
P1 pos Sources Proteases References
19 uniprot Signal peptidase
89 pmap 15066986
100 pmapuniprot 3413110 15066986
106 merops+pmap ADAM17 15066986
187 merops+pmapuniprot ADAM17 , Amphiregulin 15066986
252 uniprot

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Sequence

252 aa
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