HSA Human Sheddome Atlas
UniProt · Membrane protein

EPCAM (Epithelial Cell Adhesion Molecule)

P16422 · 314 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·14 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

10 unique positions · 14 annotations · 9/10 (90%) covered by peaks
Sources (filter in the plot above): schaeffer22paperuniprotmerops
P1 pos Sources Proteases References
18 schaeffer22 36313163
21 paperschaeffer22 33796845 36313163
22 schaeffer22 36313163
23 schaeffer22uniprot Signal peptidase 36313163
51 schaeffer22 36313163
80 schaeffer22 36313163
81 meropsschaeffer22 KLK4 15389820 36313163
163 schaeffer22 36313163
214 paper 33796845
250 schaeffer22 36313163

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Sequence

314 aa
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