HSA Human Sheddome Atlas
UniProt · Membrane protein

ITGA6 (Integrin Alpha-6)

P23229 · 1130 aa ·Signal peptide ·1× TM · 7 predicted cleavages ·20 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

12 unique positions · 20 annotations · 12/12 (100%) covered by peaks
Sources (filter in the plot above): meropsschaeffer22uniprot
P1 pos Sources Proteases References
23 meropsschaeffer22uniprot XS26.001 , Signal peptidase 2542022 36313163 1953640 2649503
525 schaeffer22 36313163
633 merops PLAU 17303120
634 uniprot PLAU in invasive prostate cancer 17303120
635 meropsschaeffer22 CLE_UNK 25564618 36313163
636 uniprot Processed integrin alpha-6 17303120
637 schaeffer22 36313163
684 schaeffer22 36313163
938 uniprot Integrin alpha-6 heavy chain
941 merops FURIN , PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7 8760366 18505722
942 uniprot Integrin alpha-6 light chain
946 schaeffer22 36313163

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Sequence

1130 aa
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