HSA Human Sheddome Atlas
UniProt · Membrane protein

FAS (Tumor Necrosis Factor Receptor Superfamily Member 6)

P25445 · 335 aa ·Signal peptide ·1× TM · 2 predicted cleavages ·18 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

9 unique positions · 18 annotations · 8/9 (89%) covered by peaks
Sources (filter in the plot above): ascentschaeffer22weeks21uniprotmerops+pmap
P1 pos Sources Proteases References
21 ascentschaeffer22weeks21 33536314 36313163 33526672
22 schaeffer22 36313163
25 schaeffer22uniprot Signal peptidase 36313163
36 merops+pmap MMP7 15077180
48 merops+pmapschaeffer22weeks21 MMP7 15077180 36313163 33526672
51 schaeffer22 36313163
52 schaeffer22weeks21 36313163 33526672
55 schaeffer22weeks21 36313163 33526672
76 ascentschaeffer22weeks21 33536314 36313163 33526672

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Sequence

335 aa
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