HSA Human Sheddome Atlas
UniProt · Membrane protein

NOTCH2 (Neurogenic Locus Notch Homolog Protein 2)

Q04721 · 2471 aa ·Signal peptide ·1× TM · 5 predicted cleavages ·13 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

8 unique positions · 13 annotations · 8/8 (100%) covered by peaks
Sources (filter in the plot above): uniprotschaeffer22topfindascentpaperweeks21hprd
P1 pos Sources Proteases References
25 uniprot Signal peptidase
360 schaeffer22 36313163
1608 topfindascentpaperschaeffer22weeks21 23264352 33536314 33796845 36313163 33526672
1622 schaeffer22 36313163
1651 schaeffer22 36313163
1662 schaeffer22weeks21 36313163 33526672
1665 hprd 11518718
1666 uniprot Notch 2 extracellular truncation

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Sequence

2471 aa
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