HSA Human Sheddome Atlas
UniProt · Membrane protein

APLP2 (Amyloid Beta Precursor Like Protein 2)

Q06481 · 763 aa ·Signal peptide ·1× TM · 1 predicted cleavages ·18 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

12 unique positions · 18 annotations · 6/12 (50%) covered by peaks
Sources (filter in the plot above): schaeffer22uniprotpaperascentweeks21merops
P1 pos Sources Proteases References
31 schaeffer22uniprot Signal peptidase 36313163
33 paper 33796845
37 ascentweeks21 33536314 33526672
38 schaeffer22 36313163
39 ascentschaeffer22weeks21 33536314 36313163 33526672
43 schaeffer22 36313163
140 merops MEP1B 21693781
182 paper 33796845
357 paper 33796845
456 paper 33796845
477 paper 33796845
662 ascentweeks21 33536314 33526672

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Sequence

763 aa
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