HSA Human Sheddome Atlas
UniProt · Membrane protein

DAG1 (Dystroglycan 1)

Q14118 · 895 aa ·Signal peptide ·1× TM · 6 predicted cleavages ·20 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

11 unique positions · 20 annotations · 6/11 (55%) covered by peaks
Sources (filter in the plot above): ascentuniprotweeks21schaeffer22papermeropsmerops+uniprot
P1 pos Sources Proteases References
29 ascentuniprotweeks21 Signal peptidase 33536314 33526672
489 schaeffer22 36313163
557 paper 33796845
575 schaeffer22 36313163
586 schaeffer22 36313163
653 meropsuniprot DAG1 , Alpha-dystroglycan , autolysis 12798792 17905726
692 schaeffer22 36313163
703 schaeffer22 36313163
715 ascentmerops+uniprotweeks21 MMP9 33536314 19946898 33526672
716 ascentweeks21 33536314 33526672
717 ascentweeks21 33536314 33526672

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Sequence

895 aa
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