UniProt · Membrane protein

MEP1A (Meprin a Subunit Alpha)

Q16819 · 746 aa ·Signal peptide ·Propeptide ·1× TM · 5 predicted cleavages ·26 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

8 unique positions · 26 annotations · 2/8 (25%) covered by peaks

Sources (filter in the plot above): uniprothprd+pmapmeropspmap

P1 pos	Sources	Proteases	References
`21`	uniprot	Signal peptidase	—
`65`	hprd+pmapmeropsuniprot	KLK5 , KLK4	12189145 18627343 15389820
`561`	merops	MEP1A	21693781
`562`	merops	MEP1A , MEP1B	21693781
`563`	merops	MEP1A	21693781
`564`	merops	MEP1A	21693781
`567`	merops	MEP1A , MEP1B	21693781
`653`	meropspmap	FURIN , PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7	18505722 7626036

746 aa

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