HSA Human Sheddome Atlas
UniProt · Membrane protein

F2RL3 (Proteinase-Activated Receptor 4)

Q96RI0 · 385 aa ·Signal peptide ·Propeptide ·7× TM · 0 predicted cleavages ·21 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

9 unique positions · 21 annotations · 9/9 (100%) covered by peaks
Sources (filter in the plot above): uniprotmerops
P1 pos Sources Proteases References
17 uniprot Signal peptidase
35 merops KLK5 , KLK14 , KLK6 16885167
36 merops KLK5 16885167
37 merops KLK5 16885167
39 merops KLK6 16885167
40 merops KLK6 16885167
47 meropsuniprot KLK5 , KLK14 , CTSG , S01.151 , PRSS3 , F2 , PLG , KLK6 , thrombin or trypsin , Removed for receptor activation 16885167 10702240 18331590 17623652 15371558
49 merops KLK14 , KLK6 16885167
51 merops KLK5 16885167

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Sequence

385 aa
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