HSA Human Sheddome Atlas
UniProt · Membrane protein

ADAM12 (Disintegrin and Metalloproteinase Domain-Containing Protein 12)

O43184 · 909 aa ·Signal peptide ·Propeptide ·1× TM · 5 predicted cleavages ·7 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

2 unique positions · 7 annotations · 2/2 (100%) covered by peaks
Sources (filter in the plot above): uniprotmerops
P1 pos Sources Proteases References
28 uniprot Signal peptidase
207 meropsuniprot FURIN , PCSK4 , PCSK6 , PCSK5 , PCSK7 9642263 18505722

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Sequence

909 aa
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