UniProt · Membrane protein

CDH2 (Cadherin-2)

P19022 · 906 aa ·Signal peptide ·Propeptide ·1× TM · 8 predicted cleavages ·61 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

40 unique positions · 61 annotations · 36/40 (90%) covered by peaks

Sources (filter in the plot above): schaeffer22uniprotweeks21meropstopfind

P1 pos	Sources	Proteases	References
`24`	schaeffer22	—	36313163
`25`	schaeffer22uniprotweeks21	Signal peptidase	36313163 33526672
`103`	schaeffer22	—	36313163
`121`	weeks21	—	33526672
`159`	meropsuniprot	KLK4	15389820
`385`	schaeffer22weeks21	—	36313163 33526672
`386`	schaeffer22weeks21	—	36313163 33526672
`387`	weeks21	—	33526672
`421`	schaeffer22	—	36313163
`430`	schaeffer22weeks21	—	36313163 33526672
`431`	schaeffer22	—	36313163
`438`	schaeffer22	—	36313163
`457`	schaeffer22	—	36313163
`458`	schaeffer22	—	36313163
`460`	schaeffer22weeks21	—	36313163 33526672
`461`	schaeffer22weeks21	—	36313163 33526672
`462`	schaeffer22weeks21	—	36313163 33526672
`463`	schaeffer22weeks21	—	36313163 33526672
`485`	weeks21	—	33526672
`487`	schaeffer22weeks21	—	36313163 33526672
`489`	schaeffer22	—	36313163
`512`	schaeffer22weeks21	—	36313163 33526672
`513`	schaeffer22	—	36313163
`515`	schaeffer22weeks21	—	36313163 33526672
`516`	schaeffer22weeks21	—	36313163 33526672
`517`	schaeffer22weeks21	—	36313163 33526672
`518`	schaeffer22weeks21	—	36313163 33526672
`519`	schaeffer22weeks21	—	36313163 33526672
`526`	schaeffer22	—	36313163
`533`	schaeffer22weeks21	—	36313163 33526672
`536`	schaeffer22	—	36313163
`537`	schaeffer22weeks21	—	36313163 33526672
`550`	schaeffer22	—	36313163
`555`	schaeffer22	—	36313163
`556`	schaeffer22weeks21	—	36313163 33526672
`637`	schaeffer22weeks21	—	36313163 33526672
`667`	schaeffer22	—	36313163
`676`	weeks21	—	33526672
`799`	topfind	—	23264352
`823`	topfind	—	23264352

906 aa

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