HSA Human Sheddome Atlas
UniProt · Membrane protein

DSG1 (Desmoglein-1)

Q02413 · 1049 aa ·Signal peptide ·Propeptide ·1× TM · 7 predicted cleavages ·13 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

10 unique positions · 13 annotations · 4/10 (40%) covered by peaks
Sources (filter in the plot above): uniprotmerops
P1 pos Sources Proteases References
23 uniprot Signal peptidase
49 meropsuniprot KLK4 , FURIN 15389820 12586364
146 merops KLK5
197 merops KLK1
242 merops KLK5
368 merops KLK6
422 merops KLK5 , KLK6
445 merops KLK1
528 merops KLK14
888 merops CASP3 16286477

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Full JSON

Sequence

1049 aa
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