HSA Human Sheddome Atlas
UniProt · Membrane protein

ADAM8 (Disintegrin and Metalloproteinase Domain-Containing Protein 8)

P78325 · 824 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·13 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

13 unique positions · 13 annotations · 12/13 (92%) covered by peaks
Sources (filter in the plot above): uniprotschaeffer22merops
P1 pos Sources Proteases References
16 uniprot Signal peptidase
44 schaeffer22 36313159
136 schaeffer22 36313159
137 schaeffer22 36313159
138 schaeffer22 36313159
157 schaeffer22 36313159
159 schaeffer22 36313159
160 schaeffer22 36313159
161 schaeffer22 36313159
167 schaeffer22 36313159
200 merops FURIN 18505722
404 schaeffer22 36313159
573 schaeffer22 36313159

Downloads

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Sequence

824 aa
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